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本研究中,作者将维生素B_1注入大鼠侧脑室或腹腔,均表现出镇痛作用。此镇痛作用可被由外周或中枢注入的纳洛酮所对抗,说明维生素B_1的镇痛作用与中枢和外周存在的阿片受体的结合有关。
In this study, the authors injected vitamin B1 into the lateral ventricle or abdominal cavity of rats and showed analgesia. This analgesic effect may be counteracted by peripheral or centrally injected naloxone, suggesting that the analgesic effect of vitamin B 1 is related to the binding of opioid receptors present in the central and peripheral tissues.