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目的:调查孕妇对唐氏综合征(DS)产前筛查服务的依从性,探讨影响DS产前筛查服务的因素,为提高DS产前筛查率提供依据。方法:对1 221例孕晚期孕妇进行问卷调查,应用SPSS 17.0软件对数据进行统计学分析。结果:收回有效调查问卷1 180份,接受DS产前筛查者704例(59.7%),未接受DS产前筛查者476例(40.3%)。多因素Logistic回归分析显示文化程度、户籍与家庭月收入是影响孕妇接受DS产前筛查的影响因素(P<0.05)。未行DS筛查的主要原因为不知晓(42.9%)、认为没必要(22.7%)、费用过高(12.6%)。结论:孕妇DS产前筛查依从性偏低,有必要加强DS产前筛查重要性,尤其是在农村地区,应降低筛查费用,以提高DS筛查依从性,降低DS患儿出生风险。
OBJECTIVE: To investigate the compliance of prenatal screening services for Down Syndrome (DS) in pregnant women and to explore the factors influencing prenatal screening services in order to provide a basis for improving prenatal screening rate. Methods: A total of 1 221 pregnant women of the third trimester were surveyed by questionnaire. SPSS 17.0 software was used to analyze the data. RESULTS: Of the 180 valid questionnaires retrieved, 704 received prenatal screening (59.7%) and 476 (40.3%) did not receive DS prenatal screening. Multivariate Logistic regression analysis showed that educational level, monthly household registration and family income were the influencing factors for prenatal screening of pregnant women receiving DS (P <0.05). The main reason for not having DS screening was unknown (42.9%), no need (22.7%), high cost (12.6%). Conclusions: The prenatal screening of prenatal DS in pregnant women is low and it is necessary to strengthen the importance of prenatal DS screening. In rural areas in particular, screening costs should be reduced to improve DS screening compliance and reduce the risk of DS in children .