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目的:了解乌鲁木齐地区汉族与维吾尔族无偿献血者Rh阴性表现型的差异,为临床Rh阴性患者筛选相合血液提供数据。方法:采用4个批号抗-D鉴定Rh阴性,用Rh分型试剂血清分别检测Rh阴性献血者红细胞的Rh表型。结果:Rh阴性者共1 396例,其中汉族705例,ccdee的表型频率为60.28%、Ccdee的表型频率为24.97%、ccdEe的表型为5.68%、CcdEe的表型为4.82%、CCdee的表型频率为3.26%、CCdEe的表型频率为0.57%、ccdEE的表型频率为0.28%、CcdEE的表型频率为0.14%;维吾尔族691例,ccdee的表型频率为86.11%、Ccdee的表型频率为10.13%、ccdEe的表型频率为2.60%、CcdEe的表型频率为0.87%、CCdee的表型频率为0.29%。结论:汉族Rh阴性C和E抗原频率明显高于维吾尔族。为临床安全输血提供资料,已经建立完整的Rh阴性献血者资料库。
Objective: To understand the difference of Rh-negative phenotype among Han and Uygur blood donors in Urumqi and to provide data for screening Rh-matched patients with Rh-negative blood. Methods: Rh-negative was identified by four batches of anti-D and the Rh phenotypes of Rh-negative blood donors were detected by Rh typing serum. Results: There were 1 396 Rh-negative cases, of which 705 cases were Han nationality, the phenotype frequency of ccdee was 60.28%, the Ccdee phenotype frequency was 24.97%, the ccdEe phenotype was 5.68% and the CcdEe phenotype was 4.82% The phenotype frequency of CCdEe was 0.57%; the phenotype frequency of ccdEE was 0.28%; the phenotype frequency of CcdEE was 0.14%; the phenotype frequency of 691 cases of Uyghur and ccdee was 86.11% The phenotype frequency was 10.13%, the phenotype frequency of ccdEe was 2.60%, the phenotype frequency of CcdEe was 0.87%, and the phenotype frequency of CCdee was 0.29%. Conclusion: The frequencies of Rh-negative C and E antigens in Han are significantly higher than those in Uighur. To provide information on clinical transfusion safety, a complete database of Rh-negative blood donors has been established.