Kashin-Beck Disease(KBD)最初于1849年由俄国在西伯利亚东部发现,Kashin和Beck先后做过调查并报道,所以称为Kashin-Beck Disease(KBD)。国外KBD见于俄罗斯的西伯利亚和朝鲜北部山区。KBD在我国称为大骨节病,属地方性畸形性骨关节病,主要分布在14个省(区)的302个县(市),病区人口近1亿,现症病人二百多万。KBD是在环境致病因素作用下,激活 Kashin-Beck Disease (KBD) was first discovered by Russia in eastern Siberia in 1849, and Kashin-Beck Disease (KBD) was investigated and reported successively. Foreign KBD is found in Russia’s Siberia and North Korea’s northern mountains. KBD in our country is called Kashin-Beck disease, which is endemic degenerative joint disease, mainly distributed in 302 counties (cities) in 14 provinces (districts). The population of the ward is nearly 100 million, and there are more than 2 million patients. KBD is activated by environmental pathogenic factors