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目的探讨米索前列醇宫腔内放置预防术中及术后子宫出血的效果。方法选择滁州市第一人民医院2012年9月-2013年4月有产后出血高危因素的剖宫产病例180例,随机分为实验组和对照组各90例,其年龄、孕周、孕次、产次、手术指征以及伴有产后出血高危因素与实验组无明显差异,实验组剖宫产术中宫体注射缩宫素20 U并宫腔放置米索前列醇0.4 mg,对照组剖宫产术中宫体注射缩宫素20 U,比较两组在术中及术后2 h总出血量,样本资料采用t检验。结果实验组在术中及术后2 h总出血量均少于对照组。两组数据差异有统计学意义(P<0.05)。结论剖宫产术中米索前列醇宫腔放置能有效预防剖宫产术中及术后子宫出血,其方法简便,效果显著。
Objective To investigate the effect of misoprostol intrauterine placement on prevention of intraoperative and postoperative uterine bleeding. Methods 180 cases of cesarean section who had the risk of postpartum hemorrhage in Chuzhou First People’s Hospital from September 2012 to April 2013 were randomly divided into experimental group and control group with 90 cases each and their age, gestational age, gestational times , Birth position, surgical indications and high risk factors associated with postpartum hemorrhage no significant difference with the experimental group, experimental group cesarean section uterine injection of oxytocin 20 U and misoprostol 0.4 mg, control group Gong Palace intrauterine injection of oxytocin 20 U, compared two groups during and after 2 h total bleeding, sample data using t test. Results The total amount of bleeding in the experimental group at 2 h after operation was less than that in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion Misoprostol in uterine cavity during cesarean section can effectively prevent uterine bleeding during and after cesarean section. The method is simple and effective.