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麻醉大鼠静脉注射CGRP后平均动脉压和总外周阻力降低,左室内压上升最大速率和左室收缩压峰值增高。这些作用在左冠状动脉结扎后较结扎前更为明显。
The average arterial pressure and total peripheral resistance decreased, the maximum rate of increase of left ventricular pressure and the peak of left ventricular systolic pressure increased after intravenous injection of CGRP into anesthetized rats. These effects were more pronounced after ligation of the left coronary artery than before ligation.