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目的 :通过对晚期或复发性妇科恶性肿瘤介入治疗的疗效分析 ,评价该方法的临床应用价值。方法 :对 4 0例妇科恶性肿瘤病人 (子宫颈癌 2 2例 ,子宫体癌 6例 ,卵巢癌 9例 ,平滑肌肉瘤 1例 ,恶性葡萄胎 2例 )采用一侧股动脉插管双侧髂内动脉灌注化疗药物并栓塞肿瘤血管治疗。每例病人插管 1～ 4次 ,总共插管 98次。在髂内动脉灌注 3～ 4种化疗药物。结果 :按照世界卫生组织对肿瘤治疗制定的统一标准判断疗效 :完全缓解 15例 ,部分缓解 12例 ,无变化 9例 ,病变进展 4例。总有效率 (CR +PR)为 6 7.5 %。所有病人均获得不同程度的近期疗效。结论 :介入治疗既可以术前缩小肿瘤 ,以利于手术切除 ,又可作为综合治疗方法之一和延长病人的寿命 ,其方法简单、安全、有效、副作用小 ,是治疗妇科恶性肿瘤一种比较理想的非手术方法。
Objective: To evaluate the clinical value of this method through the analysis of curative effect of interventional treatment of advanced or recurrent gynecological malignancies. Methods: Forty-four cases of gynecological malignant tumor patients (22 cases of cervical cancer, 6 cases of uterine body cancer, 9 cases of ovarian cancer, 1 case of leiomyosarcoma, 2 cases of malignant mole) Intraarterial infusion of chemotherapy drugs and embolization of tumor vascular treatment. Each patient intubated 1 to 4 times, a total of 98 intubation. In the internal iliac artery infusion of 3 to 4 kinds of chemotherapy drugs. Results: The curative effect was judged according to the unified standard set by World Health Organization for the treatment of cancer: complete remission in 15 cases, partial remission in 12 cases, no change in 9 cases and pathological changes in 4 cases. The total effective rate (CR + PR) was 6 7.5%. All patients received different degrees of near-term efficacy. Conclusion: Interventional therapy can reduce the tumor preoperatively to facilitate surgical resection, but also as one of the comprehensive treatment and prolong the life of patients, the method is simple, safe, effective, with fewer side effects, is a kind of ideal treatment for gynecologic malignancies Non-surgical method.