吸1支香烟,尼古丁进入全身循环的量约为1mg,与咀嚼2mg及4mg尼古丁口香糖时向血中移行的尼古丁量大致相同。但是,吸烟后血中尼古丁的浓度在2分钟内迅速达到最高值,而在服用尼古丁口香糖时则需要15～30分钟。尼古丁的血中半衰期有个体差异,但一般认为30分钟左右。每小时吸烟1支,尼古丁的血中最高浓度可达30～50ng/ml。 Benowitz等将14名嗜烟者分为两组,采用含尼古丁2mg或4mg的口香糖,对服用尼古丁口香糖时尼古丁的体内移行动态进 Suck a cigarette, the amount of nicotine into the systemic circulation is about 1mg, chewing 2mg and 4mg nicotine chewing gum into the blood when the amount of approximately the same amount of nicotine. However, the concentration of nicotine in the blood after smoking is rapidly reaching its highest value in 2 minutes, while taking nicotine gum for 15 to 30 minutes. Nicotine blood half-life there are individual differences, but generally think about 30 minutes. 1 cigarette per hour, the highest concentration of nicotine in the blood up to 30 ~ 50ng / ml. Benowitz and other 14 smokers will be divided into two groups, using nicotine 2mg or 4mg of chewing gum, nicotine nicotine nicotine in vivo migration dynamics