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近年来,我们采用酚妥拉明辅助治疗婴幼儿肺炎22例,与对照组30例比较,疗效较好。两组患儿均根据以下标准确诊:①5岁以内小儿(尤其是2岁以内者)既往无哮喘史;②突然起病,喘憋,呼吸困难,两肺满布哮鸣音;③嗜伊红细胞不高;④X线透视肺纹理增多,有点状阴影,部分病例有肺气肿。其患儿的发病年龄、临床表现、X线及化验检查基本相似。治疗采用酚妥拉明及综合治疗(如抗生素、氨茶碱、非那根、激素、毒毛旋花素K等对症治疗)。酚妥拉明用药指征为:①肺部喘鸣音明显,中细湿罗音密集,X线检查有明显改变;②严重缺氧,面色发灰、口唇、指(趾)端发绀,呼吸困难,烦躁不安或嗜睡;③合并心力衰竭。用法为:将酚妥拉明1毫克/公斤体重/次溶于5～10%葡萄糖
In recent years, we use phentolamine adjuvant treatment of infantile pneumonia in 22 cases, compared with the control group of 30 cases, the effect is better. Both groups of children were diagnosed according to the following criteria: ① children younger than 5 years old (especially within 2 years of age) had no previous history of asthma; ② sudden onset, wheezing, dyspnea, wheezing in both lungs; ③ eosinophil Not high; ④ X-ray findings increased lung texture, a bit shadow, some cases of emphysema. The age of onset of their children, clinical manifestations, X-ray and laboratory tests were similar. Treatment with phentolamine and comprehensive treatment (such as antibiotics, aminophylline, phenanthrene, hormones, poisonous furoban K and other symptomatic treatment). Phentolamine medication indications: ① lung wheezing was obvious, dense wet rales, X-ray examination significantly changed; ② severe hypoxia, pale, lip, finger (toe) side of the cyanosis, breathing Difficulty, irritability or drowsiness; ③ heart failure. Usage: Phentolamine 1 mg / kg body weight / time dissolved in 5 to 10% glucose