组织多肽抗原(tissue polypeptide antig-en,TPA)广泛存在于恶性肿瘤、胎儿体内及胎盘等。近来由于TPA-RIA方法的普及,TPA作为肿瘤标记物而得到广泛应用。有报告发现在肝脏疾病、前列腺肥大症及肾功不全等良性疾病息者TPA值亦很高。作者注意到糖尿病患者TPA值很高,就TPA值与糖尿病的并发症、网膜病变、损害及神经症状的关系进行研究。 Tissue polypeptide antigens (TPA) are widely found in malignancies, in the fetus and in the placenta. Recently, due to the popularity of the TPA-RIA method, TPA has been widely used as a tumor marker. There are reports of TPA values ​​in patients with benign diseases such as liver disease, benign prostatic hyperplasia and renal insufficiency. The authors note that patients with diabetes have high TPA values ​​and are investigating the relationship between TPA values ​​and complications of diabetes, retinopathy, damage and neurological symptoms.