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本文对43例急性白血病患者初发、完全缓解(CR)、复发时的血清甲状腺激素进行了检测。结果:初发、复发的患者血清TT_3明显低于正常对照组(P值分别<0.01、0.001),而TT_4、FT_4I及TSH无显著性改变;复发组rT_3高于正常值。在CR期,所有指标接近正常(P>0.05)。这种不伴TSH升高的低T_3可能即为病态甲状腺综合征中的低T_3综合征。低T_3综合征与疾病分期有关,并与Karnofsky健康状况相关。我们认为该综合征是疾病时的一种保护机制,建议低T_3综合征可作为急性白血病分期的参考。
In this paper, 43 cases of acute leukemia in patients with initial, complete remission (CR), serum thyroid hormone at the time of relapse were detected. Results: The serum TT_3 of newly diagnosed and relapsed patients was significantly lower than that of normal controls (P <0.01 and 0.001 respectively), but no significant changes of TT_4, FT_4I and TSH. The recurrence rT_3 was higher than normal. At CR, all the indicators were close to normal (P> 0.05). This low T 3 without elevated TSH may be the low T 3 syndrome in the pathological thyroid syndrome. Low T 3 syndrome is associated with the stage of the disease and with Karnofsky health status. We believe that the syndrome is a protective mechanism of disease, the proposed low T 3 syndrome can be used as a reference for the staging of acute leukemia.