目的 :评价共焦点显微镜对亲水性软性角膜接触镜片上蛋白质沉淀情况的观察作用。方法 :选用G Ⅰ 类和G Ⅳ类镜片为观察对象 ,分别对镜片的表面和内部进行共焦点扫描。结果 :蛋白质沉淀主要沉积在镜片的内部 ,经过洗脱处理后 ,沉淀团块变小、变分散。结论 :共焦点显微镜可对角膜接触镜片蛋白质沉淀实施快速、三维实时观察 ,并能够用来观察护理过程对沉淀形态的影响。 Objective: To evaluate the effect of confocal microscopy on protein precipitation on hydrophilic soft contact lenses. Methods: G Ⅰ and G Ⅳ lenses were selected as the observation object, and the confocal scanning was performed on the surface and inside of the lens respectively. Results: The protein precipitate was mainly deposited inside the lens. After the elution, the pellet became smaller and became more dispersed. CONCLUSIONS: Confocal microscopy enables rapid, three-dimensional real-time observation of protein precipitates in contact lenses and can be used to observe the effect of the nursing process on the morphology of the pellet.