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目的:总结儿童误服降压药急性中毒的临床特点及治疗经验。方法:收集我院误服急性降压药中毒患儿共17例,分析其临床表现及诊治过程。结果:17例患儿均有嗜睡或烦躁、血压下降,16例心动过速,1例心动过缓,血糖升高3例,血钾下降3例,血钠下降2例,外周血白细胞升高7例。所有患儿均予以洗胃、快速大量补液、静脉药物升压,3例进行血浆置换。16例患儿治愈出院,1例死亡。结论:降压药急性中毒患儿均有意识障碍、血压下降、血容量不足表现,治疗关键是及早发现、减少毒物吸收、促进毒物排泄、保持生命体征稳定。
Objective: To summarize the clinical features and treatment experience of acute poisoning of children with hypotensive drugs. Methods: A total of 17 children with acute antihypertensive drug poisoning in our hospital were collected and analyzed for clinical manifestations and diagnosis and treatment. Results: All the 17 children had drowsiness or irritability, decreased blood pressure, 16 cases of tachycardia, 1 case of bradycardia, 3 cases of hyperglycemia, 3 cases of hypokalemia, 2 cases of hyponatremia, 7 cases. All children were given gastric lavage, a large number of rapid rehydration, intravenous drug boost, 3 cases of plasma exchange. Sixteen patients were cured and discharged, and one patient died. Conclusion: Children with acute poisoning of hypotensive drugs all have disturbance of consciousness, blood pressure drop and lack of blood volume. The key to treatment is early detection, reducing the absorption of poison, promoting the excretion of poison, and keeping the vital signs stable.