论文部分内容阅读
目的探讨腹膜后脂肪肉瘤生物学行为及诊断与治疗的有关问题。方法回顾性分析1970-2005年中国医科大学附属第一医院收治的32例(共接受手术43例次)原发及复发腹膜后脂肪肉瘤病人的临床和病理资料。结果该病主要临床表现是腹胀、腹部包块进行性增大。复发病例较原发病例生物学行为差,肿瘤侵袭力强,组织学亚型恶性程度高,手术完全切除率低。多次复发者复发间期逐渐缩短。难治性大出血是术后主要且致命的并发症。结论腹膜后脂肪肉瘤术后易复发,很少转移,手术切除是最有效的治疗手段。完全切除者复发间期长,控制术中出血是减少术后死亡的关键。放、化疗对腹膜后脂肪肉瘤的作用有限。
Objective To investigate the biological behavior of retroperitoneal liposarcoma and its related problems in diagnosis and treatment. Methods The clinical and pathological data of 32 patients with primary and recurrent retroperitoneal liposarcoma treated in the First Affiliated Hospital of China Medical University from 1970 to 2005 were retrospectively analyzed. Results The main clinical manifestations of the disease were abdominal distension and abdominal mass. The recurrence of cases than the primary biological behavior of poor, strong invasive tumor, histological subtype of high degree of malignancy, complete resection rate of surgery. Repeated relapse relapse interval gradually reduced. Refractory bleeding is the major and fatal complication after surgery. Conclusion Retroperitoneal liposarcoma is easy to recur after surgery, rarely metastases, surgical resection is the most effective treatment. Complete resection of relapse interval is long, the control of intraoperative bleeding is to reduce the key to postoperative death. Put, chemotherapy on the role of retroperitoneal liposarcoma is limited.