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第三代头孢菌素(简称TGC)有显著的广谱抗菌活性,而当今使用的所有TGC,都由胃肠道外用药,因此,对严重感染或复合微生物感染的经验性治疗,引人注意,本文讨论的6种TGC是头孢噻肟(CTX)、头孢唑肟(CZX)、头孢三嗪(CTRX)、头孢哌酮(CPZ),以及Ceftazidime(CAZ),广泛经验证实这些药物并无严重副作用,但是,受与通常归因于这些抗生素所致副作用相似的那种和疾病有关不良作用混淆的影响,却是值得注意的,所有TGC不良作用总发生率,特别是和氨基糖苷类相比时是低
The third generation of cephalosporins (referred to as TGC) has a significant broad-spectrum antimicrobial activity, and all TGCs used today are administered parenterally. Therefore, the empirical treatment of severe infections or composite microbial infections is notable, The six TGCs discussed in this article are CTX, CZX, CTRX, CPZ, and Ceftazidime (CAZ), and extensive experience has demonstrated that these drugs have no serious side effects , However, it is noteworthy that the effect of confusion with the disease-related adverse effects similar to those usually attributable to these antibiotics is grossly related to the overall incidence of adverse effects of TGC, especially when compared to aminoglycosides Is low