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总结了16例急性白血病合并DIC患者的临床资料,除2例未治外,余均在化疗同时以肝素抗凝,DIC痊愈6例,好转5例,有效率7857%。化疗与抗凝在治疗中相辅相成。DIC发生时,化疗不要停止,尽量完成疗程以解除原发病,缓解DIC。在消耗性低凝期时,应用肝素时如KPTT明显延长,则需补充凝血因子。以试管法凝血时间延长1倍做为肝素化判断指标,一般勿需积极抗纤溶。DIC缓解后肝素减量要慢。对于高白细胞型白血病或M3型白血病预防性应用肝素非常必要。
The clinical data of 16 cases of acute leukemia complicated with DIC were summarized. In addition to 2 cases without treatment, Yu was treated with heparin anticoagulation at the same time. DIC cured 6 cases, improved 5 cases, and the effective rate was 78. 57 percent. Chemotherapy and anticoagulation complement each other in treatment. When DIC occurs, do not stop chemotherapy, try to complete the course of treatment to relieve the primary disease and relieve DIC. In the period of consumptive hypocoagulation, when KPTT is significantly prolonged when heparin is applied, coagulation factors need to be added. The tube coagulation time is prolonged by 1 time as an indicator of heparinization, and it is generally not necessary to actively antifibrinolysis. After DIC remission, heparin reduction should be slow. It is necessary for prophylactic heparin for high leukocyte leukemia or M3 leukemia.