1　胰岛素抵抗与新药的研发人们目前已共识 ,2型糖尿病的发病 ,常用胰岛素分泌双曲线定律来表述 ,即胰岛素敏感性和胰岛素分泌缺陷是发病的两大要素。有人调查在大量群体中约有 2 5 %的个体存在胰岛素抵抗 ,在 2型糖尿病的人群中 ,胰岛素抵抗的发病率高达 75 %～ 85 %。也有人 1 insulin resistance and the development of new drugs People have now been agreed that the incidence of type 2 diabetes, commonly used hyperinsulinism to express the law, that is, insulin sensitivity and insulin secretion defects are the two major elements of the disease. Someone surveyed about 25% of the individuals in a large number of groups had insulin resistance, and in the population of type 2 diabetes, the incidence of insulin resistance was as high as 75% -85%. There are also people