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目的:探讨解脲支原体感染与早产儿血液系统、炎症反应、肺部损伤的关系。方法:对2010年1～12月该院收治的早产儿采集痰液进行解脲支原体检测,检出49例阳性患儿(阳性组),另外选择80例阴性患儿(对照组),比较两组血常规、IL-6、IL-8、胸片、胎膜早破率。结果:阳性组白细胞总数(19.12±1.52)×109/L、IL-6(47.19±1.50)pg/ml、IL-8(18.81±1.21)pg/ml、胸片异常率为45.80%、胎膜早破率为53.60%,均高于对照组(P<0.05)。结论:解脲支原体感染与早产儿血液系统、炎症反应、肺部损伤有关,早产儿应尽早行UU-DNA检测,并结合血常规、IL-6、IL-8、胸片结果综合分析,予早期诊断和治疗。
Objective: To investigate the relationship between Ureaplasma urealyticum infection and the blood system, inflammatory reaction and lung injury in premature infants. Methods: From January to December 2010, sputum was collected from premature infants admitted to our hospital for detection of Ureaplasma urealyticum. 49 positive children (positive group) and 80 negative children (control group) were also detected. Group of blood routine, IL-6, IL-8, chest X-ray, premature rupture of membranes. Results: The total number of leukocytes in the positive group was (19.12 ± 1.52) × 109 / L, IL-6 (47.19 ± 1.50) pg / ml and IL-8 was 18.81 ± 1.21 pg / The rate of premature rupture was 53.60%, both higher than the control group (P <0.05). Conclusion: Mycoplasma urealyticum infection is associated with the blood system, inflammatory reaction and lung injury in premature infants. UU-DNA detection should be done as soon as possible in premature infants, combined with the results of blood routine, IL-6, IL-8 and chest radiograph Early diagnosis and treatment.