永靖县先天性缺陷相关因素的分析

来源 :中国自然医学杂志 | 被引量 : 0次 | 上传用户:lb19900527
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目的了解永靖县先天性缺陷的发生情况并探讨其影响因素。方法对永靖县全县(19个乡镇)进行普查,从计划生育技术服务站、医院、妇幼保健站等机构及入户调查获取2003年、2004年出生儿(包括引产、死胎和死产儿)及其父母的情况,进行病例对照分析。结果收回有效问卷2 793份,先天性缺陷74例,发生率为26.49‰,其中活产儿57例,出生缺陷发生率为20.41‰;对先天性缺陷的相关因素运用单因素分析进行初步筛选,再将筛选的因素引入多因素非条件Logistic回归分析模型,得到先天性缺陷的主要影响因素为胎位异常、孕母镇静止吐药服用史、抗生素服用史、父母血缘关系。结论永靖县出生缺陷发生率与甘肃省和全国平均水平的差异无统计学意义;先天性缺陷的影响因素具有多元性。应继续加强孕期宣教,使育龄妇女了解孕期可能出现的并发症及其危害性,减少有生理缺陷儿的出生,提高人口素质。 Objective To understand the occurrence of congenital defects in Yongjing County and its influencing factors. Methods A total of 19 counties in Yongjing County were surveyed. The births (including induced labor, stillbirth and stillbirths) in 2003 and 2004 were obtained from institutions such as family planning technical service stations, hospitals, maternal and child health care stations, and household surveys. And their parents, case-control analysis. Results There were 2 793 valid questionnaires and 74 cases of congenital defects. The incidence rate was 26.49 ‰, of which 57 were live births and the incidence of birth defects was 20.41 ‰. Univariate analysis was used to screen the related factors of congenital defects. The factors of screening were introduced into the multivariate non-conditional Logistic regression model. The main influencing factors of congenital defects were the abnormal fetal position, the taking history of sedative and antiemetic drugs, the taking history of antibiotics and the blood relationship of parents. Conclusion The incidence of birth defects in Yongjing County is not statistically different from that of Gansu Province and the national average. The influencing factors of congenital defects are diverse. Should continue to strengthen education during pregnancy so that women of childbearing age understand the possible complications during pregnancy and its harmfulness, reduce the birth of children with physical defects and improve the quality of the population.
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