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目的探讨曲昔匹特治疗小儿胃溃疡的疗效及安全性。方法胃溃疡患儿共118例,随机分为两组,其中治疗组59例,对照组59例。治疗组予以法莫替丁、曲昔匹特口服及对症治疗,对照组予以法莫替丁、硫糖铝口服及对症治疗。结果两组治疗后症状、体征缓解率、胃镜下溃疡总S期和S2期获得率治疗组均明显高于对照组,(P<0.05);治疗组治疗前后ALT及BUN测定差异无统计学意义(P>0.05)。结论曲昔匹特治疗小儿胃溃疡安全、有显著疗效。
Objective To investigate the efficacy and safety of trexipide in the treatment of gastric ulcer in children. Methods A total of 118 children with gastric ulcer were randomly divided into two groups, 59 cases in the treatment group and 59 cases in the control group. Patients in the treatment group received famotidine and traxipat orally and symptomatically, while those in the control group were given famotidine, sucralfate and symptomatic treatment. Results After treatment, the symptom and symptom relieving rate, the total gastroscopic ulcer S phase and the yield of S2 in the treatment group were significantly higher than those in the control group (P <0.05). There was no significant difference in ALT and BUN between the two groups before and after treatment (P> 0.05). Conclusion Trexitide treatment of pediatric gastric ulcer safety, a significant effect.