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随着社会的老龄化,脑卒中的发病率急剧增高。国际间比较研究显示,我国人群的脑卒中发病率高于国际平均水平,其中缺血性卒中占60%~80%。由于目前对于脑卒中的发病机制尚未明确,且无有效的治疗方法,其病死率和致残率居高不下,已成为严重影响国计民生的重要公共卫生问题。临床医师都在积极寻找脑卒中病因,特别是寻找支持脑卒中诊断的生物标志物,这对指导脑卒中的治疗并改善患者预后具有重要的临床价值[1]。
With the aging of society, the incidence of stroke is dramatically increased. International comparative studies show that the incidence of stroke in our population is higher than the international average, of which ischemic stroke accounts for 60% to 80%. Since the current pathogenesis of stroke is not yet clear and there is no effective treatment, its mortality and morbidity remain high, which has become an important public health problem that seriously affects the national economy and the people’s livelihood. Clinicians are actively looking for the cause of stroke, in particular, to find biomarkers that support the diagnosis of stroke, which has important clinical value in guiding the treatment of stroke and improving the prognosis of patients [1].