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目的 :测定补血及滋阴中成药中微量元素铁、锰、铜、锌、的含量。探讨微量元素与临床疗效的关系。方法 :采用 95版药典中溶出度法 ,利用火焰原子吸收光谱法测定了中成药及人工胃液和肠液中微量元素的含量。结果 :9种补血药和 8种滋阴药在人工胃液和肠液中皆有较高的溶出度。以十全大补丸为例 ,进行了回收率试验 ,铁、锰、铜、锌的平均回收率为 1 0 7.0 5%、97.0 0 %、1 0 3.0 0 %和 95.85%。结论 :补血及滋阴中成药中微量元素铁、锰、铜、锌的含量较高 ,补血及滋阴药间基本上无显著性差异。
Objective : To determine the content of trace elements iron, manganese, copper and zinc in blood-enriching and Yin-negative Chinese patent medicine. Explore the relationship between trace elements and clinical efficacy. Methods : The content of trace elements in Chinese traditional medicine and artificial gastric juice and intestinal juice was determined by flame atomic absorption spectrometry using dissolution method in the 95th Pharmacopoeia. Results : 9 kinds of blood and 8 kinds of yin medicine had higher dissolution in artificial gastric juice and intestinal juice. Taking Shiquandabu Pill as an example, a recovery test was conducted. The average recoveries of iron, manganese, copper, and zinc were 107.05%, 97.00%, 13.00%, and 95.85%. Conclusion : The contents of trace elements iron, manganese, copper, and zinc in Chinese traditional medicines of blood-enriching and nourishing yin are high, and there is no significant difference between blood-enriching and nourishing yin.