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目的:探讨鼻内窥镜下治疗鼻内翻性乳头状瘤的临床治疗效果。方法:选取我院接受治疗的鼻内翻性乳头状瘤患者300例,将所有患者随机分为观察组和对照组2组,每组患者150例。对照组采用传统开放式治疗方案,打开鼻腔后尽量完全切除瘤体及连带组织;观察组采用鼻内窥镜下尽量完全切除瘤体及连带组织。分别在患者术后1、3、6、10个月和1、2年对2组患者的复发例数及复发率进行统计。结果:对2组患者进行跟踪随访,随访率为100%。2组患者术后1个月随访,对照组复发例数为4例(2.7%),观察组复发例数为1例(0.7%),差异无统计学意义,P>0.05;术后3个月对照组复发12例(8.0%),观察组1例(0.7%),差异有统计学意义,P<0.05;术后6个月对照组复发18例(12.0%),观察组3例(2.0%),差异有统计学意义,P<0.05;术后10个月对照组复发18例(12.0%),观察组6例(4.0%),差异有统计学意义,P<0.05;术后1年对照组复发20例(13.3%),观察组6例(4.0%),差异有统计学意义,P<0.05;术后2年对照组复发20例(13.3%),观察组6例(4.0%),差异有统计学意义,P<0.05;随访2年后对照组治愈患者130例(86.7%),观察组144例(96.0%),差异有统计学意义,P<0.05。随访过程中,对照组除20例复发患者外共出现流鼻血患者4例,头痛患者11例;观察组除6例复发患者外共出现轻微头痛患者5例,涕中带血患者2例。结论:应用鼻内镜进行手术治疗鼻内翻性乳头状瘤效果显著,手术方案可行,可以进一步推广应用。
Objective: To investigate the clinical effect of endoscopic nasal inverted papilloma. Methods: 300 cases of nasal inverted papilloma treated in our hospital were selected. All patients were randomly divided into observation group and control group, with two groups of 150 patients. In the control group, the traditional open treatment was used. After the nasal cavity was opened, the tumor and the connective tissue were completely resected. The observation group was completely resected by endoscopic sinus surgery. The number of cases of recurrence and the recurrence rate of the two groups were calculated at 1, 3, 6, 10 months and 1, 2 years after operation. Results: Two groups of patients were followed up, the follow-up rate was 100%. There were 4 cases (2.7%) in the control group and 1 case (0.7%) in the observation group, the difference was not statistically significant (P> 0.05); after 3 months There were 12 cases (8.0%) in the control group and 1 case (0.7%) in the observation group, the difference was statistically significant, P <0.05; in the 6 months after the operation, 18 cases (12.0%) in the control group and 3 cases in the observation group 2.0%), the difference was statistically significant, P <0.05; in the control group at 18 months after operation, 18 cases (12.0%) had recurrence and 6 cases (4.0%) in the observation group, the difference was statistically significant The control group recurred 20 cases (13.3%) in one year and 6 cases (4.0%) in observation group, the difference was statistically significant (P <0.05) The difference was statistically significant (P <0.05). There were 130 cases (86.7%) in the control group and 144 cases (96.0%) in the observation group after 2 years of follow-up, the difference was statistically significant, P <0.05. During the follow-up, 4 cases of nosebleeds and 11 cases of headache were found in the control group except 20 cases of recurrence. In the observation group, 5 cases of mild headache and 2 cases of bloody tears were found in all but 6 cases of recurrence. Conclusion: Endoscopic sinus surgery for the treatment of nasal inverted papilloma significant effect, surgical options feasible and can be further promoted.