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目的:探讨超选择性动脉溶栓治疗急性大脑中动脉脑梗死的疗效和安全性。方法:收集我院就诊或住院治疗的120例急性大脑中动脉脑梗死患者,随机分为实验组和对照组,每组60例。两组患者入院后均给予相应的治疗措施,对照组患者给予静脉溶栓;实验组患者给予超选择动脉溶栓,观察并比较两组患者治疗前后神经功能缺损评分(NIHSS)以及患者治疗后临床疗效和并发症发生率。结果:与治疗前相比,两组患者治疗后的NIHSS水平均下显著降差异具有统计学意义(P<0.05);与对照组相比,实验组患者的NIHSS水平、并发症的发生率和病死率较低而治疗有效率较高差异均具有统计学意义(P<0.05)。结论:超选择性动脉溶栓治疗急性大脑中动脉脑梗死的临床疗效以及安全性较静脉溶栓更好。
Objective: To investigate the efficacy and safety of superselective arterial thrombolysis in the treatment of acute middle cerebral artery infarction. Methods: A total of 120 patients with acute cerebral infarction of middle cerebral artery treated in our hospital or hospitalized were randomly divided into experimental group and control group, with 60 cases in each group. The patients in the control group were given intravenous thrombolysis. The patients in the experimental group were given superselective arterial thrombolysis. The NIHSS scores before and after treatment in both groups were compared and compared between the two groups after treatment Efficacy and complication rates. Results: Compared with those before treatment, the NIHSS levels in both groups were significantly decreased after treatment (P <0.05). Compared with the control group, the NIHSS level in the experimental group, the incidence of complications and Lower mortality and higher effective treatment were statistically significant differences (P <0.05). Conclusion: Superselective arterial thrombolysis in the treatment of acute middle cerebral artery infarction is more effective and safe than intravenous thrombolysis.