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尿激酶型的纤溶酶原激活物(uPA)系统uPA:它的表面受体及uPA的抑制剂(PAI-1、PAI-2)共同形成蛋白水解系统,在炎症及肿瘤浸润、转移过程中起重要作用。现就CD87的信号转导、在炎症及恶性肿瘤中的作用简要综述如下。1 CD87的结构及功能1.1 CD87的结构尿激酶型的纤溶酶原激活物受体
The urokinase-type plasminogen activator (uPA) system uPA: its surface receptor and inhibitors of uPA (PAI-1, PAI-2) together form a proteolytic system that is involved in inflammation and tumor invasion and metastasis makes an important impact. Now on the CD87 signal transduction, a brief overview of the role of inflammation and malignant tumors are as follows. 1 CD87 structure and function of 1.1 CD87 structure urokinase-type plasminogen activator receptor