据UNOS科学肾移植登记处报道,活体供者移植数从1988年的1810例上升到1994年的2861例。全美250个移植中心几乎都有活体供者移植报道。移植物存活率与受者存活率一样高。3653例HLA相同的同胞兄弟姐妹供者移植中,1年、5年存活事为95％、84％;1981例子女-父母移植中,1年、5年存活率为80％、69％。360例非配偶非亲缘关系供者移植中,移植半存活期为10年;而3653例HLA相同的同胞兄弟姐妹移植半存活期为22年。这些半存活期都显著高于尸体移植9年的半存活期(P<0.01)。282例HLA相同的同胞兄弟姐妹供者的第二次移植的1年,5年存活率为94％、80％,与HLA相同的同胞兄弟姐妹供者的第一次移植无显著差异。在1005例HLA不配合的活体供者的再次移植中,1年、5年存活分别为88％、69％,比第一次移植低2％(P=0.026)。在1932例零-HLA单倍型配合的活体供者移植中,1年、5年移植物存活率为89％、73％,半存活期为13.6年,这些结果同父母供者移植相似。不管供者对受者的关系如何,移植存活率是相似的,但移植失败的原因各不相同。父母-子女肾移植失败中,父母为受者死亡率 According to the UNOS Scientific Registry of Kidney Transplants, the number of living donor transplants rose from 1,810 in 1988 to 2861 in 1994. Almost all of the 250 transplant centers in the United States have reported transplants of living donors. The graft survival rate is as high as the recipient survival rate. 3653 cases of sibling siblings of HLA identical transplants, 1 year, 5 years of survival was 95%, 84%; 1981 children - 1 year, 5-year survival rate of 80%, 69%. Transplantation of 360 non-spouse unrelated donor grafts had a 10-year half-life, while 3653 siblings with identical HLA siblings had a half-life of 22 years. These half-lives were significantly higher than those at 9 years of autopsy (P <0.01). One year and 5-year survival rates of 282 siblings of HLA-identical siblings were 94% and 80%, respectively. There was no significant difference in the first transplant between sibling siblings of HLA-identical siblings. At 1 year and 5 years, in 1005 HLA-mismatched donor donors, the 1-year and 5-year survival rates were 88% and 69%, respectively, which were 2% lower than those of the first transplant (P = 0.026). Among the 1932 living-donor x-haploidentical donor grafts, 1-year, 5-year graft survival was 89%, 73%, and half-life was 13.6 years, all of which were similar to those of the parental donor. Survival rates are similar, regardless of donor-recipient relationships, but the reasons for graft failure vary. Parents - children kidney transplant failure, the parents for the recipient mortality