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目的:探讨术腔局部施用贝复舒(bFGF)对内镜鼻窦手术(ESS)疗效的影响。方法:对324例慢性 鼻窦炎鼻息肉患者施行ESS,分左、右鼻腔,以单纯清洁术腔(A组)和清洁术腔加局部使用bFGF(B组),对比观 察其效果。结果:经χ2检验。A组愈合率低于B组,差异有统计学意义。结论:ESS术后,术腔综合性局部处理 措施十分必要,选择合理的局部用药(如bFGF),可有效控制手术创面“去黏膜化反应”,缩短黏膜转归竞争阶段, 加速上皮化。
Objective: To investigate the effect of local application of bFGF on the efficacy of endoscopic sinus surgery (ESS). Methods: 324 cases of chronic sinusitis and nasal polyps patients ESS, left and right nasal cavity, the simple cleaning of the surgical cavity (group A) and clean the cavity plus the local use of bFGF (B group), compared the effect. Results: The χ2 test. The healing rate of group A was lower than that of group B, the difference was statistically significant. CONCLUSIONS: After ESS, comprehensive local surgical treatment is necessary. Choosing a rational local drug (such as bFGF) can effectively control the “mucosal reaction” of surgical wounds, shorten the stage of mucosal transition and accelerate the epithelization.