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目的了解云南西部边境地区健康人群登革热抗体水平状况,为制定有效登革热防治对策提供依据。方法在具有登革热本地感染病例的不同地区采集健康人群血清,并采用间接酶联免疫吸附试验分别检测登革病毒IgG和IgM抗体。结果采集的740份中国籍血清标本登革病毒IgG和IgM抗体阳性率分别为10.9%(81/740)和5.7%(42/740),两种抗体同为阳性的阳性率为0.81%(6/740);缅甸籍学生这两种登革抗体阳性率分别为12.5%(13/104)和2.9%(3/104)。登革IgG/IgM抗体阳性率在不同年龄组、性别、民族、不同国籍学生中的分布无统计学差异(P>0.05);务农人群IgG抗体阳性率高于非农人群(P<0.05);盈江县IgG抗体阳性率较高。结论云南省边境地区人群广泛存在登革病毒的既往和新近隐性感染,建议加强对边境口岸和边境地区的登革热疫情监测,开展登革热防治知识的宣传和提高当地医疗机构的诊疗水平。
Objective To understand the antibody level of dengue fever among healthy population in the western border of Yunnan Province, and to provide basis for developing effective prevention and control measures of dengue fever. Methods Serum of healthy people was collected in different areas with local cases of dengue infection and indirect immunosorbent assay (ELISA) was used to detect Dengue virus IgG and IgM antibodies respectively. Results The positive rates of dengue virus IgG and IgM in 740 Chinese serum samples were 10.9% (81/740) and 5.7% (42/740), respectively. The positive rates of both antibodies were 0.81% (6 / 740). The positive rates of these two dengue antibodies in Myanmar students were 12.5% (13/104) and 2.9% (3/104) respectively. The positive rate of dengue IgG / IgM antibody in different age groups, sex, ethnicity and nationality had no statistical difference (P> 0.05). The positive rate of IgG antibody in dengue was higher than that in non - agricultural population (P <0.05). Yingjiang County, a higher positive rate of IgG antibodies. Conclusion The past and recent latent infections of dengue virus are widespread in the border areas of Yunnan Province. It is suggested to strengthen the monitoring of dengue fever in border crossings and border areas, publicize the knowledge of prevention and treatment of dengue and improve the diagnosis and treatment of local medical institutions.