论文部分内容阅读
目的探讨儿童呼吸机相关性肺炎(VAP)的病原菌分布及耐药情况。方法总结2010年3月—2013年12月机械通气治疗113例患儿的临床资料,比较机械通气时间及重复插管等因素与VAP发生率的关系,对49例诊断为VAP患儿病原学资料进行回顾性分析。结果 113例进行机械通气的患儿有49例发生了VAP,发生率43.36%,通过统计分析发现VAP的发生于插管次数、机械通气时间密切相关;49例VAP患儿检出病原菌57株,多为耐药菌,其中革兰阴性菌48株(84.21%),主要为肺炎克雷伯菌(12株),铜绿假单胞菌(11例);革兰阳性菌9株(15.79%),主要为金黄色葡萄球菌(7株),其中耐甲氧西林株5株(8.77%)。结论 VAP的病原以革兰阴性菌为主,细菌普遍耐药。
Objective To investigate the distribution and drug resistance of pathogens in children with ventilator-associated pneumonia (VAP). Methods The clinical data of 113 children treated with mechanical ventilation from March 2010 to December 2013 were summarized. The relationship between the incidence of VAP and the factors such as mechanical ventilation time and repeated intubation was compared. Etiological data of 49 children diagnosed as VAP Retrospective analysis. Results VAP was found in 49 out of 113 patients with mechanical ventilation. The incidence of VAP was 43.36%. Statistical analysis showed that VAP was closely related to the number of intubation and mechanical ventilation time. Of the 49 VAP patients, 57 were pathogenic bacteria, 48 strains (84.21%) were gram-negative bacteria, mainly Klebsiella pneumoniae (12 strains), Pseudomonas aeruginosa (11 cases), 9 strains (15.79%) of gram- , Mainly Staphylococcus aureus (7 strains), including 5 strains of methicillin-resistant (8.77%). Conclusion The pathogens of VAP are gram-negative bacteria, and the bacteria are generally resistant.