【摘 要】
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Objective: To investigate the epidemic characteristics of multidrug resistant tuberculosis in Hainan, China, to provide basic information and theories for the prevention and control of multidrug resistant tuberculosis. Methods: A retrospective descriptive
【机 构】
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Laboratory of Tropical Biomedicine and Biotechnology, Hainan Medical University, Haikou, Haikou57119
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Objective: To investigate the epidemic characteristics of multidrug resistant tuberculosis in Hainan, China, to provide basic information and theories for the prevention and control of multidrug resistant tuberculosis. Methods: A retrospective descriptive epidemiological study was conducted. Data of multidrug resistant tuberculosis in Hainan Island from January 1, 2014 to December 31, 2019 were collected for statistical analysis. The counting data were described by frequency (percentage), and the measurement data were described by mean ± standard deviation. Chi square test was used to compare the differences between different groups. If P < 0.05, the difference was statistically significant. Results: From 2014 to 2019, the multidrug resistant rate of tuberculosis in Hainan Island was 24.9% (369 / 1484), 8.0% (63 / 791) in newly-treated tuberculosis, and 44.2% (306 / 693) in retreatedmultidrug resistant rate of tuberculosis in Hainan Island was 24.9% (369 / 1484), 8.0% (63 / 791) in newly-treatedtuberculosis, and 44.2% (306 / 693) in retreated tuberculosis. The multidrug resistant rate of newly-treated tuberculosis decreased by 0.05% per year, while that of retreated tuberculosis increased by 0.03% per year. multidrug resistant tuberculosis was mainly distributed in the city of Haikou (83 cases), Danzhou (44 cases), Wenchang (42 cases), Wanning (37 cases) and Dongfang (32 cases), accounting for 64.5% of all multidrug resistant tuberculosis. Among 369 multidrug resistant tuberculosis, 81.0% were male. The proportion of newly-treated cases was 17.1% (63 / 369), while the proportion of retreated cases was 82.9% (306 / 369), which was significantly higher than that of newly-treated cases. The multidrug resistant rate of tuberculosis in different years was different. Conclusion: The drug resistance rate of tuberculosis in Hainan Island is higher than the national average level, which needs attention. The epidemiological characteristics of multidrug resistant tuberculosis with different treatment history were different.
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