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目的研究急性脑梗死患者颅内动脉狭窄或闭塞的发生率和分布特点,以及与动脉硬化危险因素之间的关系。方法根据有无颅内动脉狭窄或闭塞,将122例急性脑梗死患者分为颅内动脉狭窄或闭塞组和无颅内动脉狭窄或闭塞组。分析颅内动脉狭窄的比例和各支动脉狭窄或闭塞的比例,分析症状性颅内动脉狭窄或闭塞的比例;比较两组年龄、性别、高血压病、糖尿病、吸烟、饮酒、血脂、血同型半胱氨酸、糖化血红蛋白等危险因素的差异;分析各支动脉狭窄或闭塞与以上危险因素的关系。结果 122例研究对象中,有颅内动脉狭窄或闭塞患者55例(45.1%),其中有症状性颅内动脉狭窄或闭塞患者36/55例(65.4%),多支动脉狭窄51/55例(92.7%)。颅内动脉狭窄或闭塞组的年龄(67.29±10.92)岁大于无颅内动脉狭窄或闭塞组(63.28±11.20)岁,差异有统计学意义(P<0.05)。大脑后动脉狭窄或闭塞患者患有糖尿病比例(58.1%)较无大脑后动脉狭窄或闭塞患者(16.7%)明显增高,差异有统计学意义(P=0.011)。结论急性脑梗死患者存在颅内动脉狭窄或闭塞的比例较高,颅内动脉狭窄或闭塞与年龄有关,大脑后动脉狭窄与糖尿病关系密切。
Objective To study the incidence and distribution of intracranial arterial stenosis and occlusion in patients with acute cerebral infarction and its relationship with the risk factors of atherosclerosis. Methods According to the presence or absence of intracranial arterial stenosis or occlusion, 122 patients with acute cerebral infarction were divided into intracranial arterial stenosis or occlusion group and no intracranial arterial stenosis or occlusion group. Analysis of the proportion of intracranial artery stenosis and the proportion of each artery stenosis or occlusion, analysis of the proportion of symptomatic intracranial artery stenosis or occlusion; compared two groups of age, gender, hypertension, diabetes, smoking, alcohol consumption, blood lipids, Cysteine, glycosylated hemoglobin and other risk factors; Analysis of the stenosis or occlusion of the arteries and the above risk factors. Results Of the 122 subjects, 55 (45.1%) had intracranial stenosis or occlusion, of which 36/55 (65.4%) had symptomatic intracranial stenosis or occlusion, and 51/55 had multiple stenosis (92.7%). The age of the intracranial artery stenosis or occlusion group (67.29 ± 10.92) years was greater than that of the group without intracranial stenosis or occlusion (63.28 ± 11.20 years), the difference was statistically significant (P <0.05). The proportion of diabetic patients with posterior cerebral artery stenosis or occlusion (58.1%) was significantly higher than those without posterior cerebral artery stenosis or occlusion (16.7%), the difference was statistically significant (P = 0.011). Conclusion There is a high rate of stenosis or occlusion of intracranial artery in patients with acute cerebral infarction. The stenosis or occlusion of intracranial artery is related to age. The posterior cerebral artery stenosis is closely related to diabetes mellitus.