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目的：了解３０ 岁以下宫颈癌的发病趋势、临床表现及预后。方法：对５７ 例３０ 岁以下宫颈癌患者的临床资料进行回顾性分析（ 研究组） ，并随机以同期５０ ～５５ 岁宫颈癌９６６ 例作对照研究（ 对照组） 。结果：本院３０ 岁以下宫颈癌新病例登记率，八十年代前为０－２ ％ （１０／４８１８） ，八十年代为１－２ ％ （８／６８３） ；九十年代为５－４ ％ （３９／７２０）（ Ｐ＜０－００１） 。研究组以接触性阴道流血为主要症状，占５６－１ ％ （３２／５７） 。对照组仅１６ ％ （１５６／９６６）（ Ｐ＜ ０－０１） ；ＨＰＶ 阳性率研究组为４５－９ ％ （１７／３７） ，对照组为１８－５ ％ （２２／１１９）（ Ｐ＜ ０－０１） 。盆淋巴转移率Ⅰ期两组分别为３３－３ ％ （５／１５） 及１１－３ ％ （３６／３２０）（ Ｐ＜ ０－０５） ；Ⅱ期分别为４６－２％ （１２／２６） 及２１－７％ （８８／４０６）（ Ｐ＜ ０－０１） 。５ 年生存率研究组０ 期、Ⅰ期、Ⅱ期、Ⅲ期依次为１００％ 、７２－９ ％ 、４３－７ ％ 和０，对照组依次为１００％ 、８４－２ ％ 、８２－７ ％ 和６５－２％ ，两组对照Ⅰ期无统计学意义，Ⅱ、Ⅲ期差异显著（ Ｐ＝ ０－０２７ ，Ｐ＝ ０－００１） ?
Objective: To understand the incidence of cervical cancer under 30 years of age, clinical manifestations and prognosis. Methods: The clinical data of 57 patients with cervical cancer under 30 years of age were retrospectively analyzed (study group) and randomly assigned 966 cervical cancer patients aged 50-55 years as control group (control group). Results: The registration rate of new cases of cervical cancer under 30 years of age in our hospital was 0-2% (10/4818) before the 1980s and 1-2% (8/683) in the 1980s and 5-4 % (39/720) (P <0-001). Study group to contact vaginal bleeding as the main symptom, accounting for 56-1% (32/57). The positive rate of HPV was 45-9% (17/37) in the study group and 18-5% (22/119) in the control group (P <0) -01). The rates of pelvic lymphatic metastasis were 33-3% (5/15) and 11-3% (36/320) respectively in stage Ⅰ and group Ⅱ (46-2%, 12/26) And 21-7% (88/406) (P <0-01). The 5-year survival rate of study group 0, Ⅰ, Ⅱ, and Ⅲ were 100%, 72-9%, 43-7% and 0 respectively, while the control group was 100%, 84-2% and 82-7% And 65-2% respectively. There was no significant difference between the two groups in stage Ⅰ and stage Ⅱ, Ⅲ (P = 0-027, P = 0-001).