病例:男,21岁。因进行性指趾肥大增粗伴头晕、乏力7年,于1990年8月24日来院诊治。患者于1984年初开始自觉双手指及足趾逐渐增粗,于1985年至1988年先后多次就诊。一直被诊断为“肢端肥大症”予以对症治疗,病情毫无好转。近半年来上述症状进行性加重,面色苍白。体检:发育不良,身高150cm,体重44kg,营养一般,重度贫血貌,智力较差,反应迟钝。面容丑陋,颞额部凸出,鼻塌增宽,唇厚舌大。皮肤(?)毛丰富。两肺听诊正常.心尖区Ⅲ级收缩期杂音,肝肋下2cm,脾 Case: Male, 21 years old. Due to progressive hypertrophy of thumb toe with dizziness, fatigue for 7 years, in August 24, 1990 to hospital for treatment. Patients began to consciously double fingers and toes gradually increased in early 1984, from 1985 to 1988 has multiple visits. Has been diagnosed as “acromegaly” to be symptomatic treatment, the disease did not improve. Over the past six months the above symptoms worsen, pale. Physical examination: dysplasia, height 150cm, weight 44kg, general nutrition, severe anemia appearance, mental retardation, unresponsive. Ugly face, temporal forehead bulge, nasal collapse widened, lip thick tongue. Skin (?) Hair rich. Auscultation of both lungs normal apex Ⅲ systolic murmur, liver ribs 2cm, spleen