β微球蛋白(β_2-mG)是体内细胞合成的低分子蛋白质,由100个氨基酸构成,是T细胞和B细胞受体的一部分。近年研究表明,血清中β_2-mG浓度不仅与肾功能密切相关,而且是移植抗原(HLA)的重要组成部分,并与淋巴细胞的表面识别功能以及杀伤细胞受体作用有关。β_2-mG在骨科中的应用报道甚少,水文对部分骨科患者进行血清β2-mG测定,并对其在骨科疾病中的变化进行探讨。 Beta-microglobulin (β_2-mG) is a low-molecular-weight protein synthesized by cells in vivo and consists of 100 amino acids and is part of T-cell and B-cell receptors. Recent studies have shown that serum β 2-mG concentration is not only closely related to renal function, but also an important component of transplantation antigen (HLA), and lymphocyte surface recognition and the role of killer cell receptors. The application of β_2-mG in orthopedics is poorly understood, and the serumβ2-mG level in some orthopedic patients is measured by hydrology. The changes ofβ_2-mG in orthopedic diseases are also discussed.