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体内生物计算模型是基于生物体内各种生化分子以特定的形式互相协作、处理信息的能力而出现的一种新的计算模型,是近年来计算机科学与分子生物学交叉产生的前沿研究领域。该领域的研究使得人们可以深入理解生物体信息处理能力以及获得对这种能力的有效操控,这在计算机科学、生物学、医学上有着深远的影响。文章介绍了近几年在体内构建分子逻辑电路、分子状态机等方面的研究进展,并对未来的发展方向进行了展望。
The in vivo biological computing model is a new computational model based on the ability of various biochemical molecules to cooperate with each other and process information in a specific form. It is a frontier research area in which computer science and molecular biology cross in recent years. Research in this area enables people to gain an in-depth understanding of the biological information processing capabilities and to gain effective control over this capability, which has far-reaching implications in computer science, biology and medicine. This article introduces the research progress in building molecular logic circuits and molecular state machines in recent years, and prospects the future development.