联合国世界卫生组织统计,全球死亡患者中,三分之一是死于不合理用药;我国每年约有20万人死于药品不良反应,家庭用药不良反应需要住院治疗的病人则多达250万人。这些庞大数字的形成原因是人们对药物不良反应不够重视,合理用药做的不够,处方中开的药物和剂量都不够准确,几乎不考虑个人耐受因素。在所有影响药物反应的因素中,遗传因素占主导作用。药物在人体内代谢的过 According to the UN World Health Organization, one third of global deaths have died of irrational drug use. About 200,000 people die of adverse drug reactions each year in our country and as many as 2.5 million people require hospitalization for side effects. . The reason for these huge numbers is that people do not pay enough attention to adverse drug reactions and do not make proper use of medicines. The prescribed medicines and doses are not accurate enough to consider the individual tolerance factors. Among all the factors that influence drug response, genetic factors play a leading role. Drugs in the human body metabolism