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测定58例糖尿病患者血清肿瘤坏死因子-α(TNF-α)含量,结果发现,糖尿病肾病患者血清TNF-α含量高于非肾病糖尿病患者,而Ⅳ期糖尿病肾病患者血清TNF-α含量最高.同时发现,血清TNF-α水平与体重指数、24h尿白蛋白水平呈正相关,与胰岛素敏感指数呈负相关.
The serum level of TNF-αin 58 diabetic patients was measured. The results showed that serum TNF-αlevel in patients with diabetic nephropathy was higher than that in non-diabetic nephropathy patients, while serum TNF-αlevel was the highest in patients with stageⅣ diabetic nephropathy. Found that serum TNF-αlevel and body mass index, 24h urinary albumin level was positively correlated, and insulin sensitivity index was negatively correlated.