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对于如何预防治疗能发展成全静脉营养(TPN)的胆汁阻塞,知道的很少,作者采用了一个肠促胰酶肽类似物-蛙皮素(ceruletide)和胰泌素,治疗一例与长期TPN有关系的患胆汁阻塞的早产儿。该女婴为双胞胎之一,剖宫产,其母亲有顽固的胆囊纤维变性。该女婴为34孕周,体重960g。出生第1天出现腹胀和胆汁性呕吐。X线照射提示有胎粪性肠梗阻和小结肠,并由手术证实。在术后第2天开始TPN。当TPN进行到第29天时,血清胆红素升高至55μmol/L(3.2mg/dl),碱性磷酸酶达到500U/L;在此以后的3周直接胆红素为111μmol/L。每天的
Little is known about how to prevent treatment of biliary obstruction that develops into TPN, and the authors used an analog of cholecystokinin, ceruletide and secretin, to treat one case of long-term TPN Relationship with bile obstruction in preterm children. The baby girl is one of the twins, caesarean section, and her mother has stubborn gallbladder fibrosis. The girl was 34 weeks pregnant, weighing 960g. Bloating and biliary vomiting on day 1 of birth. X-ray presentation of meconium ileus and small intestine confirmed by surgery. TPN started on the second postoperative day. Serum bilirubin increased to 55 μmol / L (3.2 mg / dl) and alkaline phosphatase reached 500 U / L when TPN was administered on day 29; 111 μmol / L for the three weeks thereafter. daily