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目的:评价国产注射用头孢呋辛钠治疗泌尿道细菌感染的临床疗效和安全性。方法:对30例泌尿道感染患者采用随机对照临床试验,头孢呋辛钠试验组20例,西力欣对照组10例,两组的给药方法均为1.5g/次,3次/td,疗程7~14天。结果:试验组与对照组的临床有效率均为90.0%,细菌清除率分别为88.24%与88.89%,药物不良反应率分别为9.52%与10%,两组结果光显著性差异(P>0.05)。结论:头孢呋辛钠为治疗中、重度泌尿道细菌感染的安全而有效的抗生素。
Objective: To evaluate the clinical efficacy and safety of domestic injection of cefuroxime sodium in the treatment of urinary tract bacterial infections. Methods: Thirty patients with urinary tract infection were randomized controlled clinical trials. Cefuroxime sodium test group (n = 20) and celecoxib sodium control group (n = 10) were given 1.5g / td, treatment 7 to 14 days. Results: The clinical effective rate was 90.0% in the test group and the control group, the bacterial clearance rates were 88.24% and 88.89% respectively, and the adverse drug reaction rates were 9.52% and 10% respectively Light significant difference (P> 0.05). Conclusion: Cefuroxime sodium is a safe and effective antibiotic for the treatment of moderate and severe urinary tract bacterial infections.