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目的探究表阿霉素类药物动脉血管介入术治疗前后心电图变化。方法临床选择2015年12月至2016年11月本院收治的进行表阿霉素类药物动脉血管介入术病人80例,根据应用表阿霉素类药物的应用剂量分为对照组和观察组,两组手术方式相同,每组40例,观察组表阿霉素类药物剂量为100-200mg/m2,对照组应用表阿霉素类药物剂量为201-400mg/m2,两组均治疗3个疗程,比较两组治疗前、治疗1个疗程、治疗2个疗程、治疗3个疗程后的心电图的改变。结果观察组治疗1个疗程后的心律失常及ST-T段改变检出阳性率显著低于对照组(P<0.05);观察组治疗2个疗程后的心律失常及ST-T段改变检出阳性率显著低于对照组(P<0.05);观察组治疗3个疗程后的心律失常及ST-T段改变检出阳性率显著低于对照组(P<0.05)。结论表阿霉素类药物可引发动脉血管介入手术病人出现慢性心肌缺血,导致心电图ST-T段及QRS波群异常变化。
Objective To investigate the electrocardiogram changes of epirubicin before and after arterial vascular intervention. Methods Clinical selection of 80 cases of epirubicin-induced arterial vascular intervention admitted to our hospital from December 2015 to November 2016 were divided into control group and observation group according to the dose of epirubicin used. The two groups of the same surgical approach, 40 cases in each group, the observation group epirubicin dose of 100-200mg / m2, the control group of epirubicin doses of 201-400mg / m2, two groups were treated 3 Course of treatment, compared two groups before treatment, treatment of a course of treatment, treatment of 2 courses, 3 courses of treatment of ECG changes. Results The positive rate of arrhythmia and ST-T changes in observation group after 1 course of treatment was significantly lower than that in control group (P <0.05). The arrhythmia and ST-T changes in observation group after 2 courses of treatment were detected (P <0.05). The positive rate of arrhythmia and ST-T changes in the observation group after 3 courses of treatment was significantly lower than that of the control group (P <0.05). Conclusion Epirubicin drugs can cause chronic myocardial ischemia in patients undergoing arterial vascular intervention, resulting in abnormal ECG ST-T segment and QRS complex.