Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 do

来源 :世界胃肠病学杂志:英文版 | 被引量 : 0次 | 上传用户:boosmm
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
AIM To clarify the mechanisms involved in the critical endoplasmic reticulum(ER) stress initiating unfolded protein response pathway modified by melatonin.METHODS Hepatoma cells, Hep G2, were cultured in vitro. Flow cytometry and TUNEL assay were used to
其他文献
十年沧桑。十年辉煌。当历史进入到公元1994年12月28日这一天,诞生于改革开放大潮中的广州经济技术开发区,将昂首阔步地走完十年历程。当年,广州开发区筹备小组九条好汉,踏入
在我国,继股票热和房地产热之后,出现了期货热的趋势。自1990年10月,郑州粮食批发市场第一次引入期货交易以来,经过几年的发展,尤其是在1992年底放宽期货经纪公司的登记审批
当前,物价大幅上涨,居民生活是热点话题,更重要的是部分人怀念改革开放前的物价及生活,对改革开放的成就有不同的认识,通过2010和1978的对比,客观认识改革开放居民生活的变化。
AIM To explore the pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction(DCQD) in the liver of rats with severe acute pancreatitis(SAP) based on an her
AIM To assess the clinical characteristics of patients with complicated erosive esophagitis(EE) and their associated factors.METHODS This prospective, cross-sec
AIM To investigate the therapeutic effect of hydrogen-rich water(HRW) on inflammatory bowel disease(IBD) and to explore the potential mechanisms involved.METHOD
期刊
随着我国经济的飞速发展,市场经济在我国的逐步确立,每个企业都面临着前所未有的激烈市场竞争,企业管理者已经重视到人力资源管理对于企业发展的重要性。人力资源作为企业发展不
AIM To investigate factors, including psychosocial factors, associated with alcoholic use relapse after liver transplantation(LT) for alcoholic liver disease(AL
AIM To investigate the effects of depression and anxiety on health-related quality of life(QoL)in gastroesophageal reflux disease(GERD)patients and those suffer
应用ELISA法检测36例结,直肠癌病人和正常人12例血清和粪便中的CEA,大肠癌病人的血清和粪便的阳性率分别为48.5%和67.2%,而正常人分别为2.3%和3.5%;大肠癌早期血清和粪便CEA阳性率分别为42.5%和60.7%,中,晚期无差别。