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目的:观察益肾活血片治疗肾虚血瘀型2型糖尿病的临床疗效。方法:将112例肾虚血瘀型2型糖尿病患者随机分为治疗组55例与对照组57例,2组常规进行降糖、降脂药物治疗,治疗组在此基础上加益肾活血片口服治疗。治疗2周后比较2组患者空腹血糖及餐后2h血糖,总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C),及治疗后2月糖化血红蛋白(HbA1c)的变化。结果:2组患者治疗后空腹血糖、餐后2h血糖,2月后HbA1c均较治疗前明显降低,差异有显著性意义(P<0.05);2组治疗后比较,治疗组下降幅度较对照组大,差异有显著性意义(P<0.05)。2组患者治疗前后本组内比较,TC、TG、LDL-C均明显降低,差异有显著性意义(P<0.05);治疗后2组组间比较,差异无显著性意义(P>0.05)。结论:益肾活血片配合降糖药物治疗糖尿病,在改善血糖及糖化血红蛋白,降低血脂等方面,具有良好疗效。
Objective: To observe the clinical effects of Yishen Huoxue Tablet in treating type 2 diabetes mellitus with deficiency of kidney and blood stasis. Methods: 112 cases of type 2 diabetes mellitus with kidney deficiency and blood stasis were randomly divided into treatment group (55 cases) and control group (57 cases). The two groups were given routine hypoglycemic and lipid-lowering drug treatment. On the basis of this, the treatment group received Yishenhuoxue Tablet treatment. Fasting blood glucose and postprandial blood glucose, total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and postoperative hemoglobin A1c (HbA1c) were compared between the two groups after 2 weeks of treatment. The change. Results: After treatment, fasting blood glucose, postprandial 2h blood glucose and post-2h HbA1c were significantly lower than those before treatment (P <0.05). After treatment, the decreasing rate of HbA1c in treatment group was significantly lower than that in control group The difference was significant (P <0.05). The levels of TC, TG and LDL-C in the two groups before and after treatment were significantly lower than those before treatment (P <0.05). There was no significant difference between the two groups after treatment (P> 0.05) . Conclusion: Yishenhuoxue tablets with diabetes drugs for the treatment of diabetes, in improving blood sugar and glycosylated hemoglobin, lowering blood lipids, etc., has good effect.