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以人胃腺癌ＳＧＣ－７９０１细胞为实验模型，观察了维生素Ｅ琥珀酸酯（ＶＥＳ）对其生长的抑制作用，并且采用电镜、流式细胞术和末端脱氧核苷酸标记检测了ＶＥＳ诱导ＳＧＣ－７９０１细胞凋亡情况。结果表明，２０μｇ／ｍｌＶＥＳ处理ＳＧＣ－７９０１细胞４天，细胞生长抑制率达１００％，本研究结果还显示ＶＥＳ可诱导ＳＧＣ－７９０１细胞经历凋亡，同样在２０μｇ／ｍｌ剂量下处理细胞２天，可引起８９．９６％的细胞凋亡。本研究提示在离体试验条件下ＶＥＳ是人胃癌细胞潜在的生长抑制剂
The inhibitory effect of vitamin E succinate (VES) on the growth of human gastric adenocarcinoma SGC-7901 cells was observed. The effects of VES on SGC-7901 cells were observed by electron microscopy, flow cytometry and terminal deoxynucleotidyl transferase 7901 apoptosis. The results showed that VES could induce SGC-7901 cells to undergo apoptosis when treated with 20μg / ml VES for 4 days, and the cell growth inhibition rate reached 100%. The same treatment with 20μg / ml SGC-7901 cells for 2 days, Can cause 89.96% of apoptosis. This study suggests that VES is a potential growth inhibitor of human gastric cancer cells in vitro