健脾温肾方治疗排便障碍型便秘的临床研究

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目的:研究健脾温肾方治疗排便障碍型便秘的临床疗效.方法:将68例排便障碍型便秘患者随机分为治疗组和对照组,疗程均为28d.观察比较两组临床疗效,用药前后便秘症状自评问卷、便秘患者生活质量问卷得分情况以及停药后4周和8周的便秘复发情况.结果:疗程结束后治疗组和对照组临床总有效率分别为97.1%和79.4%;与对照组比较,健脾温肾方能够显著降低大便性状、排便间隔时间、排便困难度和排便时间积分(P<0.05);降低身体不适、心理社会不适、担心和焦虑以及满意度4个维度评分(P<0.01).停药4周和8周时治疗组排便障碍型便秘的复发率明显低于对照组(P<0.05).结论:健脾温肾方对排便障碍型便秘具有较好临床疗效.“,”Objective:To evaluate the efficacy of Jianpi Wenshen prescription in treatment of defecation disorder constipation.Methods:The 68 patients with defecation disorder constipation were randomly assigned to treatment and control groups,and the treatment course of each group was 28 days.The index of constipation symptom questionnaire,the quality of life of the patients with constipation and the recurrence of constipation were compared between the two groups,after 4 weeks and 8 weeks.Results:The total effective rate was 97.1% and 79.4% respectively in treatment and control groups.Compared with the control group,Jianpi Wenshen prescription group can significantly reduce the stool,defecation interval,difficult defecation and defecation time points (P<0.05);Jianpi Wenshen prescription group can reduce physical discomfort,psychological social discomfort,worry and anxiety and satisfaction of four dimension score (P<0.01).The treatment group showed lower recurrence rate than the control group in 4 weeks and 8 weeks (P<0.05).Conclusion:Jianpi Wenshen prescription shows obvious curative effect on chronic constipation.
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