随着采用强烈化疗、联合支持疗法等治疗方法的进步 ,恶性肿瘤患者生存期有了明显改善 ,但化疗及放疗严重损害机体的免疫系统 ,特别是引起中性粒细胞减少 ,致使患者发生严重的感染。以往许多被认为非致病的细菌或霉菌可引起致命性感染[1-3 ] 。本文着重讨论中性粒细胞减少与发热 With the progress of intensive chemotherapy and combined supportive therapies, the survival of malignant tumor patients has been significantly improved. However, chemotherapy and radiotherapy seriously damage the body’s immune system, especially the neutropenia, resulting in severe infection. In the past many were considered non-pathogenic bacteria or mold can cause fatal infections [1-3]. This article focuses on neutropenia and fever