醌类化合物广泛存在于动植物体内,许多抗癌药物含有醌核。醌类可经单电子还原生成相应的的醌自由基负离子,后者可转移单电子给分子氧,产生超氧负离子基,并进一步产生对生物细胞有损伤作用的羟基自由基,这被认为是醌类化合物生物毒性的主要来源之一。抗坏血酸作为重要的生物抗氧化剂,在生物保护过程中具有十分重要的意义,本文首 Quinones are widely found in animals and plants and many anticancer drugs contain quinone nuclei. Quinones can undergo single electron reduction to generate the corresponding quinone radical anion, which can transfer single electron to molecular oxygen, produce superoxide anion radical and further generate hydroxyl radical which has damaging effect on biological cells, which is considered as One of the main sources of quinolones biological toxicity. Ascorbic acid, as an important biological antioxidant, is of great significance in the process of biological protection.