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分析１９６３～１９９４年间，经手术和病理证实的９３例具有分泌甾体激素功能的卵巢性索间质肿瘤的临床病理资料。包括颗粒细胞瘤６０例，卵泡膜细胞瘤２６例（恶性５例），睾丸母、两性母细胞瘤共６例，环管状性索间质瘤１例。结果显示：６４％病例表现出与性激素相关的临床症状和体征。４５％病例同时合并子宫内膜增殖、子宫肌瘤、内膜癌等。除２１例良性卵泡膜细胞瘤外，Ⅰ、Ⅱ、Ⅲ及Ⅳ期患者分别为４５例、８例、１８例、１例。均接受手术加化疗或放疗，其中７例因复发或转移接受多次手术，术后平均存活时间为３．９年。７２例中不足５年病例和失访者分别为１０例和６例，５６例５年存活率为６９．６％。提示：这类肿瘤有分泌甾体激素功能，并表现出相应的内分泌症状。肿瘤特点为晚期复发，复发和转移后经积极治疗仍能获得较长时间生存。
From 1963 to 1994, 93 cases of ovarian sex cord interstitial tumor secreting steroid hormone were confirmed by operation and pathology. Including granulosa cell tumor in 60 cases, 26 cases of theca cell tumor (malignant in 5 cases), testis mother, amphoblastoma in 6 cases, 1 case of annular tubulointerstitial tumor. The results showed that: 64% of cases showed sex hormone-related clinical symptoms and signs. 45% of cases combined with endometrial proliferation, uterine fibroids, endometrial cancer and so on. In addition to 21 cases of benign primary cutaneous myeloma, stage Ⅰ, Ⅱ, Ⅲ and Ⅳ were 45 cases, 8 cases, 18 cases, 1 case. All received surgery plus radiotherapy or chemotherapy. Seven of them underwent multiple surgeries due to recurrence or metastasis. The average postoperative survival time was 3.9 years. In 72 cases less than 5 years, the number of cases and the missing persons were 10 cases and 6 cases respectively. The 5-year survival rate of 56 cases was 69.6%. Tip: These tumors have the function of secreting steroid hormones, and showed the corresponding endocrine symptoms. Tumor characteristics of late recurrence, recurrence and metastasis after active treatment can still get a longer time to survive.