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动态测定50例肾移植患者术后血清细胞间粘附分子-1（Intercellularadhesionmolecule-1，ICAM-1）的含量．结果表明，术后发生急性排鼻者，血清ICAM-1值明显高于无排异反应的病人，且在血清肌酐浓度升高前1天～2天已升高，随着排异反应的控制，血清ICAM－1也恢复至排异前水平；而环孢素A（CSA）急性肾中毒患者，血清ICAM－1值无变化．结果提示，动态观察血清ICAM－1对急性排异反应的早期诊断，疗效观察以及急性排异与CSA急性肾中毒的鉴别诊断均具有一定的临床应用价值．
Dynamic determination of 50 cases of renal transplant recipients postoperative serum intercellular adhesion molecule-1 (Intercellularadhesionmolecule-1, ICAM-1) content. The results showed that patients with acute nasal discharge after surgery, serum ICAM-1 values were significantly higher than patients without rejection, and in the serum creatinine concentration increased 1 day to 2 days have risen, with the rejection control , Serum ICAM-1 also returned to the level of pre-rejection; while cyclosporine A (CSA) acute renal toxicity in patients with serum ICAM-1 values did not change. The results suggest that the dynamic observation of serum ICAM-1 for early diagnosis of acute rejection, efficacy and acute rejection and acute renal syndrome differential diagnosis of CSA have a certain clinical value.