和肽素(copeptin)是精氨酸加压素(AVP)前体的C末端部分,在血液循环中和AVP等量分泌,但在体内相比AVP较稳定,且检测较方便。最近研究发现,和肽素可以作为体内急性内应力的标志物,同时还可作为心肌梗死和心力衰竭的标志物,其对于心血管疾病诊断和排除以及评价预后,具有极高的临床应用价值。 Copeptin is the C-terminal part of arginine vasopressin (AVP) precursor secreted in the same amount as AVP in blood circulation but is more stable in vivo than AVP and more convenient to detect. Recent studies have found that copeptin can be used as a marker of acute internal stress in vivo, but also as a marker of myocardial infarction and heart failure, which has high clinical value for the diagnosis and exclusion of cardiovascular disease and prognosis.