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将80例静吸复合全麻病人随机分为A组:盐酸二氢埃托啡(DHE)组,B组:对照组,观察麻醉诱导插管、术中维持及术后恢复的比较。结果发现,A组在静注DHE稀释液后5min、10min呼吸频率明显减慢,潮气量下降,与注药前相比有权显著性差异(P<0.01)。气管插管后心血管系统的应激反应,A组血压无明显变化,B组血压变化较大,两组比较有显著性差异(P<0.05),尤其心率变化更为明显(P<0.001)。术后恢复期两组病人呼吸,循环无显著性差异(P>0.05)。采用DHE复合麻醉对循环系统影响轻微,但对呼吸有明显抑制作用。
Eighty patients with static general anesthesia were randomly divided into group A: DHE group, group B: control group. The anesthesia induced intubation, intraoperative maintenance and postoperative recovery were compared. The results showed that in group A, the respiration rate was significantly reduced and the tidal volume was decreased 5 min and 10 min after intravenous injection of DHE diluent, which was significantly different from that before injection (P <0.01). There was no significant change of blood pressure in group A, but the change of blood pressure in group B was larger than that in group B (P <0.05), especially the change of heart rate was more obvious (P < 0.001). There was no significant difference in respiration and circulation between the two groups during postoperative recovery (P> 0.05). The use of DHE compound anesthesia on the circulatory system minor, but significant inhibition of respiration.